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AM - 2201

Discuție în 'Cannabinoids' creată de Charles Darwin, 2 Mai 2014.

  1. Charles Darwin

    Charles Darwin Guest

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    AM-2201(1-(5-fluoropentyl)-3-(1-naphthoyl)indole)

    is a
    that acts as a potent but nonselective
    for the
    . It is part of the
    discovered by
    at
    .

    Reputed recreational use of AM-2201 in the United States has led to it being specifiCally listed in a proposed 2011 amendment to the
    , aiming to add a number of synthetic drugs into
    . There have been anecdotal reports of individuals experiencing
    and vomiting, at doses as small as 2 mg. As the dosage is much smaller than most other synthetic cannabinoids, users may accidentally dose too much.
    have been reported at doses exceeding 10 mg. Caution should be taken if using this substance as it is active at doses as small as 500
    , has a very steep
    , and tolerance builds up very quickly to the effects. As of November 2011, there have been no reports of Dead associated with the drug. The toxicity of AM-2201 is still a matter of debate and there may be long term side effects.

    Pharmacology

    AM-2201 is a
    for
    . Affinities are: with a
    of 1.0nM at
    and 2.6nM at
    . The 4-methyl
    probably has similar affinities.
     
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    Charles Darwin, 2 Mai 2014
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