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JWH - 250

Discussion in 'Cannabinoids' started by Charles Darwin, May 2, 2014.

  1. Charles Darwin

    Charles Darwin Guest

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    JWH-250 or (1-pentyl-3-(2-methoxyphenylacetyl)indole)

    is an
    chemical from the
    family that acts as a
    at both the
    and
    receptors, with a
    of 11nM at CB1and 33nM at CB2. Unlike many of the older
    compounds, this compound does not have a
    ring, instead occupying this position with a 2'-methoxy-phenylacetyl group, making JWH-250 a representative member of a new class of cannabinoid ligands. Other 2'-substituted analogues such as the
    ,
    and
    compounds are also active and somewhat more potent.

    History

    JWH-250 was discovered by, and named after the researcher Dr.
    . He created JWH-250 and a number of other compounds to research the structure and function of the
    system of
    . Samples of JWH-250 were first identified in May 2009 by the German Federal Criminal Police, as an ingredient in new generation "
    " that had been released since the banning of the original ingredients
    and
    . An ELISA immunoassay technique for detecting JWH-250 in urine has been reported.
     
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    Charles Darwin, May 2, 2014
    #1